赵欢

发布时间:2021-09-03 发布单位:beat365手机客户端


个人简介

    赵欢,女,博士。2017年从暨南大学药学院博士毕业,博士毕业后进入beat365手机客户端(亚洲)集团有限公司中药方剂学教研室从事教学和科研工作。主要从事方药及中药药效物质及作用机制研究,目前以第一作者或通讯作者身份发表SCI论文8篇,包括3A1类论文。主持国家自然科学基金1项,广州市基础与应用基础研究项目1项,暨南大学培育基金1项,申请并授权发明专利3项。



教学/科研成果



  课题:

[1] 主持国家自然科学基金青年基金项目炭皮属真菌来源杂萜抗阿尔茨海默症活性成分及作用机制研究818034082019-2021年,21万,在研。

[2] 主持广州市基础与应用基础研究项目莽草酸-萜途径来源杂萜抗阿尔茨海默症活性成分的优选及作用靶标研究2021-20235万,已立项。

[3] 主持暨南大学科研培育与创新基金研究项目邻苯甲酰胺苯甲酸衍生物抗阿尔茨海默病活性成分的优选与机制研究 216183362017-2020年,15万,在研。

[4] 参与国家重点研发计划冠心病(心绞痛-心肌梗死-心衰)中医药防治方案的循证优化及疗效机制2017YFC17004)中课题五冠心病防治方药的药效物质基础及作用方式研究2017YFC1700405),2017-2021年,280万,在研。

  论文:

[1] Zhao Huan#, Chen Guo-Dong, Zou Jian, He Rong-Rong, Qin Sheng-Ying, Hu Dan, Guo Liang-Dong, Yao Xin-Sheng*, Gao Hao*. Dimericbiscognienyne A: A Meroterpenoid Dimer from Biscogniauxia sp. with New Skeleton and Its Activity. Org. Lett.2017, 19 (1), 38-41. (A1SCI, Top)

[2] Zhao Huan#, Zou Jian, Xu Wei, Hu Dan, Guo Liang-Dong, Chen Jia-Xu, Chen Guo-Dong, So Kwok-Fai, Yao Xin-Sheng, Gao Hao*.Nine Diisoprenyl-cyclohexene/ane-type Meroterpenoids from Biscogniauxia sp. and Their Anti-inflammatory Activities. J. Org. Chem. 2021. (Accepted, A1SCI, Top)

[3]Zhao Huan#, Wang Mei-Zhi, Chen Guo-Dong, Hu Dan, Li En-Qing, Qu Yi-Bo, Zhou Li-Bing, Guo Liang-Dong, Yao Xin-Sheng, Gao Hao*. Dimericbiscognienynes B and C: New Diisoprenyl-cyclohexene-type Meroterpenoid Dimers from Biscogniauxia sp.. Chin. Chem. Lett.2019, 30, 51-54.(A1SCI)

[4] Zhao Huan#, Wang Gao-Qian, Tong Xu-Peng, Chen Guo-Dong, Huang Yuan-Fan, Cui Jia-Yu, Kong Ming-Zhu, Guo Liang-Dong, Zheng Yi-Zhi, Yao Xin-Sheng, Gao Hao*. Diphenyl Ethers from Aspergillus sp. and Their Anti-Aβ42 Aggregation Activities. Fitoterapia2014, 98, 77-83. (A2SCI)

[5] Yang Heng-Gang#, Zhao Huan#(co-first author), Chen Shao-Meng, Mou Lang-Ming, Zou Jian, Chen Guo-Dong, Qin Sheng-Ying, Hu Dan, Yao Xin-Sheng, Gao Hao*. Phyllomeroterpenoids A-C, Multi-biosynthetic Derived Meroterpenoids from the TCM Endophytic Fungus Phyllosticta sp. and their Antimicrobial Activities. Sci. Rep-UK2017, 7 (1): 12925-12932. (A2SCI)

[6] Liu Yan-Ying#, Zhao Huan#(co-first author), Xie Jun, Zou Jian, Hu Dan, Guo Liang-Dong, Chen Guo-Dong, Yao Xin-Sheng, Gao Hao*. New Phthalide Derivatives from the Biscogniauxia sp. and Their Activities. Fitoterapia2019, 137, 104184-104189.(A2SCI)

[7] Yuan Xu-jiang*, Liu Ya-Di, Zhao Huan#(co-first author), Men Li-Jiao, He Cui-Min, Qiu Yu,Yu Qiang-Qiang, Li Kun-Ping, Qi Long-Kai, Chen Di-Ling. The isolation, structure and fragmentation characteristics of natural truxillic and truxinic acid derivatives in Abrus mollis leaves. Phytochemistry 2021, 181, 112572-112581. (A2SCI)

[8] Liu Pei#, Deng Li#, Lv Yi-Wen, Xu Hua-Chong, Zhao Huan*, Chen Xiao-Yin*. Single Acupuncture Treatment Can Reduce the Level of Uric Acid and Alleviating Pain in Gouty Arthritis, a Meta-Analysis. Acupunct. Electrother. Res. 2021, 46, 147-158. (A2SCI)

专利:

[1] 炭皮酸A及其在制备预防和治疗神经退行性疾病药物中的应用。(授权专利号:ZL201611101594.0;授权时间:2019.05.07)

[2] 二聚炭皮烯炔A及其在制备预防和治疗神经退行性疾病药物中的应用。(授权专利号:ZL20161101694.3;授权时间:2019.07.30)

[3] 联苯醚类化合物在制备β-淀粉样蛋白聚集抑制剂中的用途(授权专利号:ZL201410332005.4;授权时间:2016.02.04




获奖及荣誉






学术兼职


1、广东省中西医结合学会转化医学专业委员会委员

2、广东省分析测试协会核磁共振专业委员会会员

3、中华中医药学会会员

4、上海中医药杂志审稿人